Characterization of a Stem-like Subpopulation in Basal-like Ductal Carcinoma in Situ (DCIS) Lesions
نویسندگان
چکیده
منابع مشابه
Ductal carcinoma in situ (DCIS) in Karachi.
OBJECTIVE To study the frequency of ductal carcinoma in situ (DCIS) in a large pathology series. DCIS is a proliferation of non-invasive, malignant epithelial cells within the ductolobular system of the breast. It is a heterogeneous entity with several morphologic variants that differ in gross appearance, growth pattern, cytologic features, mammography, and malignant potential. METHODS The da...
متن کاملIdentification of a basal-like subtype of breast ductal carcinoma in situ.
Microarray profiling of invasive breast carcinomas has identified subtypes including luminal A, luminal B, HER2-overexpressing, and basal-like. The poor-prognosis, basal-like tumors have been immunohistochemically characterized as estrogen receptor (ER)-negative, HER2/neu-negative, and cytokeratin 5/6-positive and/or epidermal growth factor receptor (EGFR)-positive. The aim of this study was to...
متن کاملDiagnosis and management of ductal carcinoma in situ (DCIS).
OBJECTIVES Systematic synthesis of the published evidence about incidence, risk factors, and management options for women with ductal carcinoma in situ (DCIS) of the breast. DATA SOURCES Original epidemiologic studies were sought from several databases to identity articles published in English between 1970 and January 31, 2009. REVIEW METHODS Incidence of DCIS in the general population and ...
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Background: Contagious ecthyma or orf is a poxviral disease of goat and sheep, with incidental infection appearing in humans, cows, camels, and many wild ruminants, and very rarely in dogs. Case description: In the present paper was described gross morphology and histopathology of contagious ecthyma in a dog with a large ulcerated cutaneous mass in the neck (under the collar) which was ma...
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A 15-year-old boy presented with several months history of bilateral axillary lymph adenopathies which were ulcerated subsequently. He had received anti-tuberculosis therapy for more than six months based on suspicious diagnosis of scrofuloderma. Histopathologic examination confirmed the diagnosis of specific lesions of Hodgkin’s disease. These lesions were probably metastatic due to retrograde...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2014
ISSN: 0021-9258
DOI: 10.1074/jbc.m113.502278